Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...
Despite an FDA green light for the use of animal testing alternatives in drug development, regulatory concerns may be keeping the industry from embracing them, data collected by the R&D organization ...
Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...
The field of biological research has long relied on conventional model animals to unravel complex biological and ...
Animal testing remains to be a vital part of modern preclinical testing. While the ethics of the use of animals in medical testing remains keenly debated, it is still generally accepted worldwide and ...
CRISPR-Cas9 technology is used to knock out or modify DNA in research mice to study disease phenotypes and develop new treatments. CRISPR mice and rats are offered by Charles River, which uses genetic ...
The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...
A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...
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