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Bridge recombinases, optimized for human cells, enable massive programmable DNA rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with ...
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with ...
(Nanowerk News) In a leap forward for genetic engineering, a team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and ...
The discovery of CRISPR-Cas9’s gene-editing prowess revolutionized genetic engineering just over a decade ago. Now it appears that genetic engineering technology may be taking its next big leap.
A molecular oddity found in bacteria could hold the key to redesigning genomes at will, allowing researchers to insert, delete or flip large segments of DNA. Guided by an RNA molecule called a ‘bridge ...
In the past decade or so, biomedical technology has been revolutionized by a gene editing technique known as CRISPR, which uses a guide RNA molecule to direct a DNA-cutting enzyme to a specific ...
A team of researchers from the Arc Institute have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way. Going far beyond ...
This figure depicts how bridge recombinases have a dual targeting capability that enable these systems to insert new genetic material, delete unwanted regions, or flip existing DNA segments all in a ...
PALO ALTO, Calif.--(BUSINESS WIRE)--In a leap forward for genetic engineering, a team of researchers from the Arc Institute has discovered the bridge recombinase mechanism, a precise and powerful tool ...
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