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Neural organoids derived from patient-specific iPSC lines can help open doors toward studying human brain development, physiology, and disease progression. The increased cell-cell interactions in ...

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson’s disease. The model, developed by the group of Jürgen Knoblich at ...

In the study, "Human stem cell-derived A10 dopaminergic neurons specifically integrate into mouse circuits and improve depression-like behaviors," published in Cell Stem Cell, researchers developed a ...

The second higher-resolution projection focuses on the midbrain-pinpointing dopaminergic neurons with greater precision. This "comprehensive reference map" now provides scientists worldwide with a ...

Dopamine neurons in a part of the brain called the midbrain may, with aging, be increasingly susceptible to a vicious spiral of decline driven by fuel shortages, according to a study led by Weill ...

Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides ...

Researchers have genetically engineered stem cells so that they differentiate into greater numbers of the specific dopamine-producing neurons needed for effective Parkinson’s disease cell therapy. The ...

Parkinson's disease (PD) is the second most common neurodegenerative disorder, primarily characterized by motor dysfunction.

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model replicates the dopaminergic system's structure ...