UB researchers have identified for the first time an enzyme in the foxglove plant that is responsible for the production of compounds needed to make the heart failure drug digoxin. The breakthrough ...

The therapeutic efficacy of the cardiac glycoside digitoxin in patients with heart failure and reduced ejection fraction is not established. In this international, double-blind, placebo-controlled ...

BUFFALO, N.Y. — Foxglove plants, found in many gardens, are known for the showers of bell-shaped flowers they produce. But plants belonging to this genus, Digitalis, also harbor a less visible asset: ...

Digitalis has been used to treat heart failure for more than 200 years. The drug digitoxin also belongs to this group of active ingredients known as cardiac glycosides. Non-antibiotic drugs can alter ...

MADRID -- Digitoxin added to guideline-directed medical therapy improved outcomes among patients with heart failure and reduced ejection fraction (HFrEF), the DIGIT-HF trial showed. The cardiac ...

Foxglove plants are known to be shaped like bells and have long decorated many gardens. They belong to a genus of plants, Digitalis, and have been studied for a particular asset they hold—a chemical ...