This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. The work was led by Ian Maze, a neuroepigeneticist ...

Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in ...

Fruit ripening determines shelf life and consumer appeal, yet the molecular switches that control this process remain partially understood. This study identifies a key regulator—histone deacetylase ...

Tomato fruit ripening is a tightly regulated process involving hormonal signaling, metabolic reprogramming, and epigenetic modulation. Ethylene plays a pivotal role in climacteric fruit ripening, but ...