The ultimate goal of regenerative medicine is to replace lost or damaged cells. This can potentially be accomplished using the processes of dedifferentiation, transdifferentiation or reprogramming.

Liver cells exposed to a high fat diet revert to an immature state that is more susceptible to cancer-causing mutations.

Differentiation, the stepwise specialization of cells, and transdifferentiation, the apparent switching of one cell type into another, capture much of the stem cell spotlight. But dedifferentiation, ...

Researchers found that in fruit flies, intestinal cells can transform into stem cells in response to nutritional changes, expanding our understanding of dedifferentiation and its role in organ ...

Human stem cells can differentiate into any human cell. But the process of dedifferentiation, essentially differentiation in reverse, is implicated in several diseases. Now researchers have uncovered ...

Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit ...

Type 2 diabetes results from a combination of insulin resistance and dysfunction of insulin-producing pancreatic beta cells. Insulin deficiency is thought to be caused by both beta-cell dysfunction ...

A phase I trial of T4 CAR T-cell immunotherapy in head and neck squamous cancer (HNSCC). Screening of neoantigen-specific T cells and establishment of T-cell receptor-engineered T cells: Implications ...

<p><a href="/profiles/profile.jsp?id=49" target="_blank">Professor Pierre Schlag</a> is the winner of Colorado Law’s 2010 Jules Milstein Scholarship Award for his ...