At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

Researchers at the University of Washington and Fred Hutch found that CARD8, an inflammasome sensor, detects HIV-1 in macrophages during cell-to-cell viral transmissions from infected T cells. HIV can ...

Immunocore’s big swing for a functional HIV cure has cleared its first hurdle. No serious adverse events were tied to the British biotech’s bispecific T-cell engager in a phase 1/2 trial, and the ...

Around the world, some 40 million people are living with HIV. And though progress in treatment means the infection isn’t the death sentence it once was, researchers have never been able to bring about ...

Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at ...

For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating-and possibly even curing-the disease a seemingly insurmountable obstacle to achieve. But ...

Achieving lasting remission for HIV Around the world, some 40 million people are living with HIV. And though progress in treatment means the infection isn’t the death sentence it once was, researchers ...