DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
Illustration of H2B or H3 tail-less nucleosomes. Nucleosomes lacking H2B and H3 tails exhibit weakened interactions between histone tails and nucleosomal DNA, leading to less stable nucleosome ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...
Modern Engineering Marvels on MSN
140,000 DNA loops mapped with AI to predict genome folding
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
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