The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused immense suffering and economic hardship to millions of people worldwide. To date, the mechanism of infection by SARS-CoV-2 ...

Left: the two peptide chains of an integrin receptor, colored red and blue, extend through the cell membrane into the extracellular space. Center: when bound to the common form of the FN10 ligand or ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...