The different classes of diuretics have different mechanisms of action but the overall aim of diuretic therapy is to increase the amount of water excreted in the urine. Some of the mechanisms of the ...

Purpose. The management of loop diuretic resistance in the intensive care unit (ICU) is reviewed. Summary. Volume overload, a common complication of fluid resuscitation, is frequently encountered in ...

The investigators of a new study have shown that the use of loop diuretics might be an initiating factor in the early pathogenesis of secondary hyperparathyroidism. “Loop diuretics are known to ...

Impaired diuretic response is a common complication in patients with acute heart failure and is associated with increased rehospitalization and mortality compared with patients who have normal ...

Over time, the retention of sodium leads to crackles, peripheral edema, hepatomegaly with ascites, increased blood volume, and increased cardiac filling pressures. Although diuretics do not directly ...

Please provide your email address to receive an email when new articles are posted on . Acute and chronic HF are associated with sodium retention leading to volume overload and edema. Much of the ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use. In a prospective, double-blind, ...

Reducing congestion is a key element of therapy but loop diuretics exacerbate many of the core mechanisms thought to underly CRS. Through effective control of the volume status for an extended period ...