Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

Epigenetics, the modification of chromosomes without altering DNA sequences, serves as a crucial regulatory mechanism for gene expression. Among the various epigenetic marks, N6-methyladenosine (m6A) ...

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications are ...

Image Caption: The molecular mechanism of m6A methylation. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular ...

Immunologists have revealed the essential function of m6A modifications in T cells. The research group working with immunologists Vigo Heissmeyer and Taku Ito-Kureha of LMU and Helmholtz Munich has ...

N6-methyladenosine (m 6 A) is the most commonly known RNA modification, and the methylation of adenosine at the nitrogen 6 position, which causes this. It is especially found in abundance in mRNA of ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

Recent studies revealed critical roles for an abundant RNA modification in cancer biology that might offer promising molecular targets for epitranscriptomic-based therapies. RNA modifications play a ...

m6A RNA modifications could explain why females have a higher liver fat content than males, with gene therapy being a potential treatment option for liver disease. Non-alcoholic fatty liver can lead ...