Publication shows that OGM can resolve translocation partners involving MYC in multiple myeloma (MM) more effectively than current methods The release of compelling data in MM underscores the ...

Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most ...

Researchers at the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI) have found a link between a common mutation that can lead to ...

CtIP is a DNA end resection factor widely implicated in alternative end-joining (A-EJ)–mediated translocations in cell-based reporter systems. To address the physiological role of CtIP, an essential ...

Plasmablastic Morphology Is an Independent Predictor of Poor Survival After Autologous Stem-Cell Transplantation for Multiple Myeloma PURPOSE: To correlate cytogenetic abnormalities with clinical ...

The human immune system runs a risky business. It mutates its own DNA to diversify defenses against foreign invaders it has never before encountered. Unfortunately, these mutations sometimes miss the ...

Researchers at the Scripps Research Institute in Florida have made a clinical discovery that could help physicians develop new treatments for an oral cancer that affects the salivary glands, according ...

The human immune system is in a perpetual state of self-experimentation. It expertly mutates and shuffles the DNA of its own cells to evolve new defenses against the vast array of microbes that try to ...