In recent years, there has been increasing evidence that mitochondrial dysfunction plays a causative role in Crohn's disease and other gastrointestinal disorders. This can happen for a variety of ...

Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes, and make their own proteins. Mutations in mitochondrial DNA ...

Investigations in Japan have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure. Chronic heart failure causes the cell's powerhouses to dysfunction, in part ...

We identify six causal molecular biomarkers (e.g., CNPY4, ENTPD6, HLA-A) and eight clinical biomarkers (e.g., serum total protein) for MASLD across various independent cohorts. Serum total protein ...

Erectile dysfunction is a disease that affects half of American men aged over 50 years. Many men respond to oral phosphodiesterase inhibitors but many do not. For this reason, many researchers are ...