In the mutation accumulation experiment, amoebae were allowed to reproduce until they formed a visible plaque, and then one was picked at random and carried to a new plate where it was allowed to ...

Spontaneous mutations tend to reduce fitness in populations of living organisms, but this erosion of fitness is countered by natural selection. This study uses the first mutation accumulation ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 36 (September 3, 2019), pp. 17906-17915 (10 pages) Bacteria evolve by mutation accumulation in laboratory ...

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...

Experiments from the 1940s established a key tenet of genetics—mutagenesis occurs randomly across the genome. New research, however, suggests that mutations may be less random than originally thought.

An evolution experiment involving beetles has provided the first direct evidence that caring for offspring results in the accumulation of more genetic mutations in a population. Some of the mutations ...