A new study reveals intricate details about the biology of the huntingtin protein (HTT), which is responsible for Huntington's disease. The research focuses on axonal transport -- the way in which ...

Mutations on a single gene, the huntingtin gene, are the cause of Huntington's disease. They lead to an incorrect form of the correspondent protein. With the help of cryo-electron microscopy ...

A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating ...

A new therapeutic strategy for treating Huntington’s disease patients that is based on small interfering RNA (siRNA) could have fewer side effects than earlier approaches (Chem. Biol., DOI: ...

A research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. Using genetic mouse ...

Huntington’s disease may be more straightforward to fight than doctors have feared, paradoxically because the genetic brain disorder is more complicated than anyone knew, U.S. researchers said ...

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease. Using ...