Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

Understanding biological and physical processes involving nucleic acids, such as the binding of proteins to DNA and RNA, DNA condensation, and RNA folding, requires an understanding of the ion ...

Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA, ...

48. Arteaga, S. J., Dolenz, B. J., and Znosko, B. M. (2024) "Competitive influence of alkali metals in the ion atmosphere on nucleic acid duplex stability," ACS Omega ...

PITTSBURGH--For the first time, a team of investigators at Carnegie Mellon University has shown that the binding of metal ions can mediate the formation of peptide nucleic acid (PNA) duplexes from ...

Nancy J. Peffer, Jeffrey C. Hanvey, John E. Bisi, Stephen A. Thomson, C. Fred Hassman, Stewart A. Noble, Lee E. Babiss Proceedings of the National Academy of Sciences ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Nucleic acids are essential for all forms of life, and it is found in all cells. Nucleic acids come in two natural forms called deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Image Credit: ...

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour. In ...