As reviewed above, much has been learned over the past 20 years regarding the pathways that KRAS engages and requires during lung tumorigenesis, and specific inhibitors of these downstream signaling ...

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative ...

Tumor-suppressive miRNAs inhibit oncogenic pathways, preventing cancer progression, while oncogenic miRNAs promote tumor growth by targeting tumor suppressor genes. miRNA, microRNA. Lung cancer (LC) ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor ...

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...

CDK 4/6 inhibitors (CDK4/6i) remain part of the standard first-line treatment for patients with hormone receptor–positive metastatic breast cancer, offering demonstrable improvements in both ...

Cancer is the second leading cause of death worldwide, and the incidence of cancer is increasing every year. Lipids, ...

Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion, tumor heterogeneity, and immune-related adverse events.