Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

MONMOUTH JUNCTION, N.J., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company, today announced the acceptance of its peer-reviewed article "The ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Researchers at USF Health are making dramatic strides in understanding how new opioid compounds work inside the body to provide pain relief, offering greater hope that new classes of these drugs may ...

Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.

Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

Addressing overdoses from “street drugs” containing potent synthetic opioids poses a key challenge when utilizing opioid antagonists. A standard approach to known or suspected opioid overdose includes ...