ascopubs.org

Population pharmacokinetic and pharmacodynamic (PK-PD) parameters of Erwinia Chrysanthemi (ERW) asparaginase (ASNase) using the fused first-order elimination and Michaelis ...

Influence of single agent gemcitabine (GEM) schedule on the pattern of response and toxicity in patients with advanced pancreas, lung and breast carcinoma: A systematic review No significant financial ...
insideHPC

Parallel Implementation of PK-PD Parameter Estimation on Intel Xeon Phi

In this video from the 2015 HPC Advisory Council Switzerland Conference, Nishant Kumar Agrawal from Tata Consultancy Services presents: Parallel Implementation of PK-PD Parameter Estimation on Xeon ...
ascopubs.org

Imatinib Plasma Levels Are Correlated With Clinical Benefit in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumors

To study the pharmacokinetics (PK) of imatinib (IM) in patients with advanced GI stromal tumors (GISTs) treated in a randomized phase II study and to explore the potential relationship between IM ...
PharmTech

The Power of PK/PD in mAb Development

Although well known in R&D, PK/PD studies are an equally powerful tool for promoting successful biologic drug development. An understanding of the pharmacokinetics (PK) of monoclonal antibodies (mAbs) ...
PharmTech

PK/PD Studies Prove Critical for mAb Development

PK/PD studies are a crucial tool in the successful development of biologics. An understanding of the pharmacokinetics (PK) of monoclonal antibodies (mAbs) is important so that potential patient ...