Polymorphisms of thymidylate synthase as prognostic factor in rectal cancer. Background: Tumour cells have been shown to express exclusively the embryonic M2 isoform of pyruvate kinase (PKM2), which ...

A multicenter phase III randomized double-blind placebo controlled trial of pravastatin added to first-line standard chemotherapy in patients with small cell lung cancer (SCLC). This is an ASCO ...

In 2024, an estimated 310,720 women in the United States will be diagnosed with invasive breast cancer -- and about 80% of breast cancers are estrogen-receptor-positive, or ER+ breast cancer, making ...

Crippling a protein that allows cancer cells to grow when oxygen is scarce causes tumors to regress, according to a study published online on January 23 in the ...

Low-dose aspirin significantly reduced colorectal cancer recurrence in patients with PI3K pathway gene alterations, nearly halving recurrence rates over three years compared to placebo. The study ...