The enzyme PP1 has a key role in many of the body's healthy functions and diseases. It's so generally important that drug developers dare not target it. In a new study, scientists report a big leap in ...
The serine/threonine protein phosphatase 1 (PP1) dephosphorylates hundreds of key biological targets. PP1 associates with ≥200 regulatory proteins to form highly specific holoenzymes. These regulatory ...
Mitotic exit comprises all the mitotic stages after 'satisfaction' of the spindle assembly checkpoint, including chromosome segregation, cytokinesis and reassembly of interphase cell structures.
A study describes how neurons activate the protein PP1, providing key insights into the biology of learning and memory. A study in The Journal of Cell Biology describes how neurons activate the ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 24 (Jun. 15, 2004), pp. 8888-8893 (6 pages) Inhibition of myosin phosphatase is critical for ...
PROVIDENCE, R.I. [Brown University] — In the Proceedings of the National Academy of Sciences, a team of scientists at Brown University reports a major step forward in determining the specific behavior ...