In the current work, we demonstrate that Syk is overexpressed in the majority of PTCLs, despite the absence of SYK/ITK translocations in most cases. As one orally available Syk inhibitor 14 is already ...
Activating the cell surface receptor TREM2 rallies microglia to clear amyloid plaques. Can activating a kinase downstream of TREM2 do the same? Two groups of scientists say yes. In the October 26 Cell ...
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