For more than 80 years, men have been told that testosterone helps prostate cancer grow. But a very different picture has ...

A University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in ...

A major international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men. The research, published in ...

A newly uncovered mechanism thought to be a weakness of prostate cancer cells could inspire a new and improved targeted treatment for the disease. International research led by Flinders University in ...

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

Researchers have identified a gene that plays a key role in prostate cancer cells that have transitioned to a more aggressive, treatment-resistant form. The gene can be indirectly targeted with an ...

Researchers have discovered that prostate cancer depends on two key enzymes, PDIA1 and PDIA5, to survive and resist therapy. When blocked, these enzymes cause the androgen receptor to collapse, ...

A new research paper was published in Volume 16 of Oncotarget on June 25, 2025, titled "Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer." In this study ...

Scientists based in Australia and China have identified a pair of pesky enzymes responsible for prolonging prostate cancer – which means we can potentially target them for quicker and more effective ...

In cancer, the e1F4a enzyme forces cells to make tons of cancerous proteins. A UCSF team found that the breast cancer drug, zotatifin, turns e1F4a, which normally assists in protein production, into a ...