In the search for effective antivirals to prevent and treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, scientists have investigated the possibility of inhibiting the main ...

Enzyme 'atlas' helps researchers decipher cellular pathways Biologists have mapped out more than 300 protein kinases and their targets, which they hope could yield new leads for cancer drugs ...

You might think of tuberculosis (TB) as a disease of the past, similar to polio or smallpox. In fact, it is the world’s most infectious killer, according to the World Health Organization, causing an ...

A new AI model designs peptides (short proteins) that are targeted by enzymes called proteases, which are overactive in cancer cells. Nanoparticles coated with these peptides can act as sensors that ...

Pfizer is developing an oral drug to prevent COVID-19 infections. This drug, currently known as PF-07321332, is a protease inhibitor "designed to block the activity of the main protease enzyme that ...

On Oct. 10, the Schroeder Lab, led by Prof. Frank Schroeder, chemistry and chemical biology, published a study detailing a new class of serotonin-containing compounds and another serotonin pathway in ...

When bacteria die, their bodies rupture and spill a buffet of nutrients for neighboring microbes. The live cells feast on molecules served by their dead counterparts and in turn become a meal for ...