The Golgi apparatus transports and modifies proteins in eukaryotic cells. How have scientists studied dynamic protein movements through the Golgi? One of the principal observations by Rothman's group ...

Microtubules are central to the spatial organization of diverse membrane-trafficking systems. Here, we report that Hook proteins constitute a novel family of cytosolic coiled coil proteins that bind ...

Rice glutelin polypeptides are initially synthesized on the endoplasmic reticulum (ER) membrane as a proglutelin, which are then transported to the protein storage vacuole (PSV) via the Golgi ...

Scientists have long sought a robust picture of how the Golgi complex, an organelle critical to the post-translational modification and sorting of newly synthesized proteins, operates. The Golgi ...

The cell must provide its various organelles with all the energy elements they need, which are formed in the Golgi apparatus. But how do the proteins that carry these cargoes - the kinesins - find ...

Researchers design and trace a modified cholera toxin to cell organelles for insights on glycoprotein trafficking inside compartments of cells Proteins usually undergo modifications during or after ...

The secretory pathway in eukaryotic cells is crucial for maintaining cellular function and physiological activities, as it ensures the accurate transport of proteins to specific subcellular locations ...

In a recent study published in Retrovirology, researchers assessed the effectiveness of severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 envelope (E) proteins against human ...

In a recent study posted to the bioRxiv* preprint server, researchers observed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) downregulates the expression of major histocompatibility ...

Scientists have discovered a new contender in the quest to hack the human aging process, and it’s a little-studied protein within a cell structure that also doesn’t get a lot of airtime in research ...