Researchers have identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition of a Heat shock ...

An estimated 20 percent of adults in the US experience chronic pain. 1 To help patients manage their condition, clinicians have employed one main type of pain-relieving drug: opioids. With their ...

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from ...

Researchers have discovered a blood signature of protein isoforms that could potentially predict which patients may reject a new organ transplant, helping inform therapeutic decisions. The findings of ...

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called ...

UCLA-led researchers identified a molecular switch that prevents lung blood vessel repair in bronchopulmonary dysplasia.

Researchers have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a target for future ...

Research shows protein isoform inhibitors may hold the key to making opioids safer A new University of Arizona Health Sciences-led study identified a viable path to developing a novel therapy that ...