One of the most important classes of human enzymes are protein kinases - signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction ...

A cross-institutional effort between researchers at Weill Cornell Medicine and Duke University has yielded exciting progress in the search for new therapeutics against Covid-19. Where much of our ...

Proteins are often called the building blocks of life. While true, the analogy evokes images of Lego-like pieces snapping together to form intricate but rigid blocks that combine into muscles and ...

Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins. When these switches are stuck in the ...

In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. But there are hundreds of ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...

A team has identified a protein that modifies the cellular machinery responsible for producing cellulose, which could inform the design of more stable, cellulose-enriched materials for biofuels and ...

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that ...

Researchers have shown that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum enabled it to infect humans. Researchers from the Francis Crick ...