Chemical modifications to DNA and RNA play critical roles in gene regulation, development, viral infection, and human disease, including cancer and neurological disorders. More than 150 epigenetic and ...
A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases ...
Researchers at LMU have elucidated why certain RNA modifications do not trigger an immune response—a key mechanism for RNA therapeutics. The innate immune system is the body's first line of defense ...
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