To initiate transcription, the holoenzyme (RNA polymerase [RNAP] in complex with σ factor) loads the promoter DNA via the flexible loading gate created by the clamp and β-lobe, yet their roles in DNA ...
In a recent preprint* uploaded to the bioRxiv server, researchers developed and trained a foundational model to predict tissue-specific RNA expression, splicing, RNA binding protein specificity, and ...
Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Atomic AI, a biotechnology company fusing cutting-edge machine learning with state-of-the-art structural biology to unlock RNA drug discovery, announced ...