Open Heart

Mineralocorticoid receptor antagonists for acute myocardial infarction: a systematic review and meta-analysis of randomised controlled trials

Background The role of mineralocorticoid receptor antagonists (MRAs) in acute myocardial infarction (MI) remains ...
Fierce Biotech

FDA steers cancer CAR-T developers toward randomized superiority trials in policy shift

The FDA is raising the bar for approval of CAR T-cell therapies in oncology. | The FDA is raising the bar for approval of CAR ...
BioSpace

CAR-T Developers Will Need Randomized Trials as FDA Eyes Tighter Approval Requirements

For traditional approval, CAR T therapies will need to establish superiority over current standard treatments, including ...
BMJ Open

Prospective randomised controlled trial of the use of nasogastric tubes in patients with adhesive small bowel obstruction (ASBO): protocol for the NASBO study

Introduction Nasogastric tubes (NGTs) are standard practice in the management of adhesive small bowel obstruction (ASBO). Their insertion can be associated with significant patient discomfort and ...

Special breathing tubes don't improve emergency intubation outcomes, trial finds

Modified endotracheal tubes designed to reduce patient pneumonia risk failed to improve outcomes compared to standard ...
BMJ Open

Pilot randomised controlled trial of the self-help plus stress management intervention among patients with breast and gynaecological cancer in Viet Nam: a study protocol

Introduction Implementation of low-intensity, evidence-based psychological interventions can help meet the mental health and ...
JSTOR Daily

Can Randomized Controlled Trials Be Remedied?

Daedalus, Vol. 154, No. 2, The Ethics of Social Research: Perspectives from the Study of the Middle East & North Africa (Spring 2025), pp. 157-168 (12 pages) As the Middle East and North Africa (MENA) ...