Plasmids, small circular DNA molecules found in bacteria, may contain antibiotic-resistance genes and have the ability to replicate independently. Bacteria can transfer these plasmids to one another, ...

Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...

DNA-based information is a new field hoping to fill the gap in long-term data storage by using DNA as an information storage medium. Despite DNA’s potential, researchers face problems accurately ...

Nucleic acid purification procedures have enjoyed a long history, beginning with the first isolation of "nuclein" in 1869 by Freidrich Meischer. In 1958, Matthew Meselson and Frank Stahl demonstrated ...

Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication. Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication, according to Thomas Wood, ...