USA: Researchers have found in a new study that de-escalation of empiric broad-spectrum antibiotic therapy on day 4 in ...

Clinical outcomes among adult inpatients were no worse when broad-spectrum antibiotic therapy was delayed vs started early, challenging the belief that overly broad-spectrum empiric antibiotic therapy ...

The Pediatric Infectious Diseases Society and the Infectious Diseases Society of America published a guideline in 2011 detailing recommended treatment for children with community-acquired pneumonia ...

Individual risk assessment with automated electronic health record alerts are an effective and safe strategy to limit use of extended-spectrum antibiotics in patients hospitalized with UTI. An ...

About half of suspected sepsis cases account for broad-spectrum antibiotic use — but a lot of these cases don’t require the medications at all, according to a study published June 27 in JAMA Network ...

Among adults treated for community-acquired pneumonia in the outpatient setting, broad-spectrum antibiotics vs macrolide monotherapy were associated with an increased risk for adverse drug events.

Antibiotic resistance is an important issue and a priority for UK health policy. It's possibly the next ticking time bomb in the healthcare system. In our analysis, the financial burden of the tax is ...

For pediatric patients with uncomplicated appendicitis, what is the best choice of antibiotic therapy for preventing surgical-site infection and lowering the frequency of hospital revisits? Overall, ...

A key property of many antibiotics is that they will kill or inhibit a diverse range of microbial species. This broad-spectrum of activity has its evolutionary roots in ecological competition, whereby ...