DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...
An important specialty in this field—and a signature area of study at the University at Albany's RNA Institute—is DNA nanotechnology, wherein the base pairs that comprise DNA molecules are manipulated ...
Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...
New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
In a world-first study, we have revealed and analysed remarkably preserved fragments of ancient DNA from the skin of a woolly mammoth. For the first time, we’ve been able to understand how the genetic ...
For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.
Researchers posit that changes in the three-dimensional structure of DNA inside brain cells may play a key role in ...