Potent single-molecule inhibition of all major classes of EGFR activating and resistance mutations, including C797X and T790M, with a high degree of kinome and wild-type EGFR selectivity Deep and ...

Lazcluze demonstrated significant CNS activity, regardless of T790M status, in treating intracranial and leptomeningeal metastases in patients with EGFR-variant NSCLC. For patients with metastatic ...

Cancer genetics evaluation among individuals at risk for Lynch syndrome across all qualifying indications. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...

Researchers at ETH Zurich in Basel report they have used CRISPR-Cas technology to decipher how mutations in a cell’s genome affect its function. With their new approach, the researchers can generate ...

Consistent with previous observations, overall survival and progression-free survival remained strong at the follow-up point. The phase 3 trial found that adding chemotherapy to gefitinib improved PFS ...

NEW YORK (Reuters Health) - Whether variant forms of a gene called EGFR increase or decrease survival with colon cancer depends on whether the patient is male or female, new study findings indicate.

Please provide your email address to receive an email when new articles are posted on . Patients with EGFR-mutated NSCLC who received osimertinib had an elevated risk for therapy-related cardiac ...