That Aβ begets tau pathology is the central premise of the amyloid cascade hypothesis of Alzheimer’s disease. But how exactly does the begetting happen? A paper published August 31 in Cell Reports ...

Bipolar disorder (BD) is a psychiatric disorder characterized by extreme mood changes. Individuals diagnosed with BD ...

This is a preview. Log in through your library . Abstract Ca²⁺ channel β subunits determine the transport and physiological properties of high voltage-activated ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

Synaptic pruning is the process in which the brain removes neurons and synapses that it does not need. This usually takes place when a person is 2–10 years old. The brain contains millions of neurons ...

Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...