Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

This figure presents the volcano plots for visualizing DEGs (a) and the functional enrichment analyses (b-d) for upregulated and downregulated DEGs in the immune non-responder (INR) group vs. healthy ...

This article is based on a poster originally authored by Weiping Sun, Xing Zhang, Zhaolu Yan, Chen Yu, Spencer Chiang, and Tianfu Zhang. Immunotherapy is an advanced and widely used treatment due to ...

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...

A study published in Nature Communications examined the use of calcium carbonate nanoparticles (CNPs) to improve the activation and function of cytotoxic T lymphocytes (CTLs) in cancer immunotherapy.

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

A diagram illustrating the potential functions of ADA2 transported to endolysosomes of monocytes/macrophages and secreted externally from the cells. Adenosine deaminase 2 (ADA2) plays a critical role ...

Marker Therapeutics, Inc. has announced a collaboration with Cellipont Bioservices to support the cGMP manufacturing of MT-601, its lead Multi-Antigen Recognizing (MAR)-T cell therapy, currently in ...