Genome-wide approaches are used to discover the RNA-binding targets of the amyotrophic lateral sclerosis (ALS) disease protein FUS/TLS. These studies reveal some shared targets with another ALS-linked ...

WORCESTER, Mass. — Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal ...

Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study shows that a common pathway links them. Two proteins previously found to ...

Researchers have identified a novel genetic cause of inherited amyotrophic lateral sclerosis, the fourth gene associated with familial forms of the devastating neurological disorder. A collaborative ...

BOSTON – A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King’s College London (KCL) has identified a novel gene for inherited ...