Transient receptor potential canonical channels are essential for maintaining the function of human pulmonary endothelial cells in PAH.

Microvascular endothelial dysfunction is an early or inductive event that occurs in the development of cardiovascular diseases and associated organ damage. The endothelium is composed of a single ...

Sepsis is a life-threatening condition that often leads to ARDS, characterized by widespread inflammation and vascular injury. This study identifies lactate-driven lysine lactylation (Kla) as a ...