The Trypanosoma brucei cysteine protease cathepsin B (TbCatB), which is involved in host protein degradation, is a promising target to develop new treatments against sleeping sickness, a fatal disease ...

The parasite Trypanosoma brucei causes sleeping sickness. It evades human defences by changing the version of a protein that coats its surface. Analysis of its genome and nuclear structure clarifies ...

Sleeping sickness is caused by infection of humans and livestock by various forms of Trypanosoma brucei (T.b.) parasites and is a major health and socio-economical problem in large areas of ...