A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune ...

Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why ...

The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

BATF2 is a new type of tumor suppressor that can be epigenetically silenced by high levels of glutamine in the tumor microenvironment Glutamine silences BATF2 and leads to a weakened immune response ...

A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how ...

The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...

"Using 2 complementary methods, we demonstrated that T cells in the lung tumor microenvironment do, in fact, demonstrate evidence of poor immune function." — Brinda Emu, MD, Yale University School of ...