How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Mount Sinai researchers developed a first-in-class cell-selective modRNA translation system that turns therapeutic genes on ...

KAIST researchers have developed a method that attaches DNA fragments to mRNA to slow the onset of protein production, ...

SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.

You don't want to miss this! To permanently access this eBook for free, fill out the short form below. From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

The discovery of chemical modifications to overcome mRNA’s instability and immunotoxicity have enabled mRNA therapeutics to evolve dramatically, reaching clinical trials and the forefront of modern ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

RNA, widely known from the COVID-19 vaccine, is not actually a “therapeutic agent,” but a technology that delivers the ...