Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal ...

Attrition in the therapeutic pipeline can often be associated with the lack of translational efficacy from the pre-clinical phase to the clinic. Organoids demonstrate the significant potential to ...

The intestinal parasite Cryptosporidium is a vicious trespasser, hiding within the cells that line the gut and causing intestinal damage. "Cryptosporidium infections can be life-threatening, ...

The gut–islets axis connects nutrient sensing in the intestine with insulin secretion from the pancreas and plays an ...

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the ...

Organoids with both intestinal and colonic regions are able to better represent the human GI tract with Ebola and Marburg infections.