This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A research team describes how they engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA, ...

A research team has found that compounds in the nucleic acids derived from food can inhibit the growth of certain cancer cells. When people eat, they ingest the nucleic acids that reside in all living ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of ...

In a study published in Genome Research, a team of researchers, including Cornell College Assistant Professor of Biology Sophie Gillett, looked at regions of human genetic code that are known for ...

Advances in artificial intelligence (AI)–assisted protein engineering are enabling breakthroughs in the life sciences but also introduce new biosecurity challenges. Synthesis of nucleic acids is a ...

1 Compliance and Research Innovation, University of Nevada, Reno, NV, United States 2 Tutela Strategies, LLC, Reno, NV, United States Introduction: Recent U.S. biosecurity policy has shifted from ...

Department of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, ...

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...