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  1. PDPN - Wikipedia

    PDPN, i.e., podoplanin, is a small glycoprotein located on the surface membranes of various cell types.

  2. Podoplanin: An emerging cancer biomarker and therapeutic target

    Podoplanin (PDPN) is a transmembrane receptor glycoprotein that is upregulated on transformed cells, cancer associated fibroblasts and inflammatory macrophages that contribute to cancer progression.

  3. PDPN Gene - GeneCards | PDPN Protein | PDPN Antibody

    Nov 14, 2025 · PDPN (Podoplanin) is a Protein Coding gene. Diseases associated with PDPN include Lymphangioma and Angiosarcoma. Among its related pathways are Response to elevated platelet …

  4. Frontiers | Podoplanin: emerging functions in development, the …

    Sep 12, 2012 · Podoplanin (PDPN) is a well-conserved, mucin-type transmembrane protein expressed in multiple tissues during ontogeny and in adult animals, including the brain, heart, kidney, lungs, …

  5. PDPN Central – Structure. Function. Future

    Podoplanin (PDPN) is a unique transmembrane receptor that promotes cell adhesion and motility. The PDPN receptor controls critical aspects of many processes including embryonic development, …

  6. Podoplanin mediates stromal–immune crosstalk in the lymph node

    Jan 31, 2025 · PDPN is a cell-surface marker commonly used to identify FRCs in lymph nodes. Loss of this glycoprotein during embryonic development impedes lymph node development.

  7. PDP1 (PDP-N) Gene: Function, Expression, and Research

    Learn about the PDPN gene (placental protein 13), its function in cell adhesion, angiogenesis, and cancer metastasis, and its potential as a research target and therapeutic target.

  8. Podoplanin in Inflammation and Cancer - PMC

    Podoplanin (PDPN), also known as PA2.26, gp38, T1α, D2-40, and Aggrus, is a small transmembrane mucin-like glycoprotein whose amino-acid sequence is well conserved across vertebrates.

  9. Roles of Podoplanin in Malignant Progression of Tumor - MDPI

    Feb 7, 2022 · Podoplanin (PDPN) is a cell-surface mucin-like glycoprotein that plays a critical role in tumor development and normal development of the lung, kidney, and lymphatic vascular systems. …

  10. What are PDPN inhibitors and how do they work? - Patsnap

    Jun 25, 2024 · Podoplanin (PDPN) inhibitors are an emerging area of interest in the field of medical research, particularly in oncology and inflammatory disease studies. The development of these …